Film | Rôle | Année |
|---|
| Frère des ours 2 | Kata (voice) | 2006 |
| Maman, j'ai raté l'avion ! | Kate | 1990 |
| Maman, j'ai encore raté l'avion ! | Kate | 1992 |
| Beetlejuice | Delia | 1988 |
| After Hours | Gail | 1985 |
| Rock & Rule | Aunt Edith (voice) | 1983 |
| Nos voisins, les hommes | Penny (voice) | 2006 |
| Penelope | Jessica Wilhern | 2007 |
| From Cleveland | Various | 1980 |
| Wyatt Earp | Allie Earp | 1994 |
| PMS - Premenstrual Syndrome | Mary Marcus | 1985 |
| Méli-Mélo | Beatrice Lever | 1998 |
| Le Journal | Susan | 1994 |
| L'Étrange Noël de monsieur Jack | Sally / Shock (voice) | 1993 |
| Temple Grandin | Aunt Ann | 2010 |
| Monster House | Mom (voice) | 2006 |
| The Rutles 2 - Can't Buy Me Lunch | Astro Glide | 2003 |
| Back Home Again | Mayor Owl (voice) | 2021 |
| Chicken Little | Tina - Alien Mom (voice) | 2005 |
| A Mighty Wind | Mickey Crabbe | 2003 |
| La brûlure | Betty | 1986 |
| Bêtes de scène | Cookie Fleck | 2000 |
| An Audience with Adele | Self | 2021 |
| Élémentaire | Brook (voice) | 2023 |
| For Your Consideration | Marilyn Hack | 2006 |
| Le Cadeau du ciel | April Simon | 1994 |
| Famille à louer | Christine Valco | 2004 |
| Kiss & Kill | Mrs. Kornfeldt | 2010 |
| Frankenweenie | Mrs. Frankenstein / Weird Girl / Gym Teacher (voice) | 2012 |
| The Last of the High Kings | Cathleen | 1996 |
| Waiting for Guffman | Sheila Albertson | 1997 |
| Max et les Maximonstres | Judith (voice) | 2009 |
| Witch's Night Out | Malicious (voice) | 1978 |
| Bartok le magnifique | Ludmilla (voice) | 1999 |
| Away We Go | Gloria Farlander | 2009 |
| Beetlejuice Beetlejuice | Delia | 2024 |
| Catherine O'Hara: All of Us Shine | Self | 2021 |
| The Last Polka | Lemon Twin | 1985 |
| A.C.O.D. | Melissa | 2013 |
| L'Erreur Parfaite | Tess | 2013 |
| Late Last Night | Dr. Fontes | 1999 |
| Tales from the Warner Bros. Lot | Self | 2013 |
| Intergalactic Thanksgiving, or Please Don't Eat the Planet | Ma Spademinder (voice) | 1979 |
| Orange County | Cindy Beugler | 2002 |
| The Life Before This | Sheena | 1999 |
| Marchands de douleur | Jackie | 2023 |
| Little Vegas | Lexie | 1990 |
| There Goes the Neighborhood | Jessie Lodge | 1992 |
| Wild About Books | | 2005 |
| Canada Far and Wide | Self | 2020 |
| Les Légendes de l'Ouest | Calamity Jane | 1995 |
| Hope | Muriel Macswain | 1997 |
| Le Robot sauvage | Pinktail (voice) | 2024 |
| Being Canadian | Self | 2015 |
| Easter Fever | Scarlett O'Hare (voice) | 1980 |
| Christmas with SCTV | | 2006 |
| Double Negative | Judith | 1980 |
| Edwurd Fudwupper Fibbed Big | Lorna Mae Loon (voice) | 2000 |
| Really Weird Tales | Theresa Sharpe (segment "I'll Die Loving") | 1986 |
| Les Désastreuses Aventures des orphelins Baudelaire | Justice Strauss | 2004 |
| The Wool Cap | Gloria | 2004 |
| Game 6 | Lillian Rogan | 2006 |
| The Incredible Time-Travels of Henry Osgood | Marie Antoinette | 1986 |
| Twilight Park | Queen Henrietta | |
| Nothing Personal | Audrey | 1980 |
| Speaking of Sex | Connie Barker | 2001 |
| Dick Tracy | Texie Garcia | 1990 |
| Tears Are Not Enough | Self | 1985 |
| Barbie au bal des 12 princesses | Duchess Rowena (voice) | 2006 |
| Le Mariage de Betsy | Gloria Henner | 1990 |
| La Famille Addams | Grandma Frump (voice) | 2019 |
| Les Bouchetrous | Alma (voice) | 2021 |
| John Candy: Comic Spirit | Self | 2005 |
| Best Wishes, Warmest Regards: A Schitt's Creek Farewell | Self | 2020 |
| Stronger Together, Tous Ensemble | Self | 2020 |
| The Best of SCTV | | 1988 |
| I, Martin Short, Goes Hollywood | Nancy Mae | 1989 |
| Rome, Italian Style | Ursula Schneider | 1982 |
| Searching for Debra Winger | Self | 2002 |
| Andrea Martin... Together Again | | 1989 |
| Les mômes de l'Apocalypse : Vive la fin du monde ! | | 2021 |
| Argylle | Ruth | 2024 |
| You Had to Be There: How the Toronto Godspell Ignited the Comedy Revolution... | Self (archive footage) | 2026 |
| Rabbit Ears - Finn McCoul | Narrator (voice) | 1991 |
| John Candy: I Like Me | Self - Actor, SCTV | 2025 |
| Friends of Gilda | Self | 1993 |
| Vancouver 2010 Olympic Closing Ceremony | Herself | 2010 |
| Home Alone - Making of & Behind the Scenes | Kate | 1999 |
| Good Behavior | Jackie West | 2008 |
| Martin Short : Une vie XXL | Self | 2026 |
