Film | Rôle | Année |
|---|
| Jurassic Park III | Ellie | 2001 |
| Sailor et Lula | Lula | 1990 |
| Cœurs perdus | Rene Fodie | 2006 |
| Blue Velvet | Sandy Williams | 1986 |
| Inland Empire | Nikki Grace / Susan Blue | 2006 |
| Lynch 2 | Self | 2007 |
| Docteur T & Les Femmes | Peggy Travis | 2000 |
| Mask | Diana | 1985 |
| Les Bootleggers | Sharon Anne (uncredited) | 1973 |
| Novocaine | Jean Noble | 2001 |
| A Night at the Academy Museum | Self | 2021 |
| Traqués | Teresa | 2009 |
| Ras les profs ! | Diane | 1984 |
| We Don't Live Here Anymore | Terry Linden | 2004 |
| Rambling Rose | Rose | 1991 |
| Daddy and Them | Ruby Montgomery | 2001 |
| Ladies and Gentlemen, the Fabulous Stains | Jessica McNeil | 1982 |
| Un monde parfait | Sally Gerber | 1993 |
| Les Maîtres de l'Ombre | Kathleen Robinson | 1989 |
| The Prize Winner of Defiance, Ohio | Dortha Schaefer | 2005 |
| Smooth Talk | Connie Wyatt | 1985 |
| Ciel d'octobre | Miss Riley | 1999 |
| Year of the Dog | Bret | 2007 |
| Citizen Ruth | Ruth Stoops | 1996 |
| Recomptage | Katherine Harris | 2008 |
| Haunted Summer | Claire Clairmont | 1988 |
| Happy Endings | Pam | 2005 |
| Behind the Lines | Self | |
| Grizzly II: Revenge | Tina | 2020 |
| Industrial Symphony No. 1: The Dream of the Brokenhearted | Heartbroken Woman | 1990 |
| Everything Must Go | Delilah | 2011 |
| Carol Burnett: 90 Years of Laughter + Love | Self - Guest | 2023 |
| The Siege at Ruby Ridge | Vicki Weaver | 1996 |
| Mon beau-père et nous | Prudence | 2010 |
| The Master | Helen Sullivan | 2012 |
| Ozi, la voix de la forêt | Seema (voice) | 2024 |
| Sheryl | Self | 2022 |
| La Terre à tous | Self | 2023 |
| The Making of 'Jurassic Park' | Self / Ellie Sattler | 1995 |
| The Endangered Generation? | Self (voice) | 2023 |
| Final Cut : Ladies And Gentlemen | (archive footage) | 2012 |
| The Strange Case of Dr. Jekyll and Mr. Hyde | Rebecca Laymon | 1989 |
| Down Came a Blackbird | Helen McNulty | 1995 |
| Ça plane, les filles ! | Debbie | 1980 |
| Searching for Debra Winger | Self | 2002 |
| Mysteries of Love | Self | 2002 |
| The Baby Dance | Wanda LeFauve | 1998 |
| Le Triomphe de la vérité | Janet Harduvel | 1992 |
| La saison des miracles | Berry Thompson | 1999 |
| Within These Walls | Sister Pauline Quinn | 2001 |
| The Monday Before Thanksgiving | Theresa | 2008 |
| Lonely Planet | Katherine Loewe | 2024 |
| Goose | Narrator (voice) | 2002 |
| Nos étoiles contraires | Frannie Lancaster | 2014 |
| Joyce Carol Oates, la femme aux cent romans | Voice | 2022 |
| Lynch (one) | Self | 2007 |
| Jennifer Lopez : Halftime | Self | 2022 |
| Focus | Gertrude 'Gert' Hart | 2001 |
| Jurassic Greatest Moments: Jurassic Park to Jurassic World | Self | 2022 |
| 2023 Rock & Roll Hall of Fame Induction Ceremony | Self | 2023 |
| Wild | Bobbi Grey | 2014 |
| 99 Homes | Lynn Nash | 2015 |
| Alice n'est plus ici | Girl Eating Ice Cream Cone (uncredited) | 1974 |
| When The Game Stands Tall | Bev Ladouceur | 2014 |
| Sam, je suis Sam | Randy Carpenter | 2001 |
| Dancing Heart | Annie | 2015 |
| Le Fondateur | Ethel Kroc | 2016 |
| Wilson | Pippi | 2017 |
| Jay Kelly | Liz | 2025 |
| The Force of Sound | Vice-Admiral Holdo (archive footage) | 2018 |
| In the Small, Small Pond | | 2001 |
| The Three Wishes of Billy Grier | Crissy | 1984 |
| No Frank in Lumberton | Self | 1988 |
| Jurassic Park | Ellie | 1993 |
| Certaines Femmes | Laura | 2016 |
| Le passé recomposé | Jennifer | 2018 |
| Monsanto | Dr Melinda Rogers | |
| The Hill Chris Climbed: The Gridiron Heroes Story | Self | 2011 |
| Jonathan Ross Presents for One Week Only: David Lynch | Self | 1990 |
| Damaged Care | Linda Peeno | 2002 |
| Star Wars : Les Derniers Jedi | Vice Admiral Holdo | 2017 |
| Downsizing | Laura Lonowski | 2017 |
| J.T. LeRoy | Laura Albert | 2019 |
| The Black Ghiandola | Doctor | 2017 |
| The Good Time Girls | Clementine | 2017 |
| The Words That Built America | Self - Reader: Declaration of Independence | 2017 |
| Spielberg | Self | 2017 |
| L'épreuve du feu | Elizabeth Gilbert | 2019 |
| Bobbi Jene | Self | 2017 |
| Marriage Story | Nora Fanshaw | 2019 |
| Trespassing Bergman | Self | 2013 |
| Blue Velvet Revisited | Self | 2016 |
| Fight for Your Right Revisited | Cafe Patron | 2011 |
| The Director and the Jedi | Self | 2018 |
| Sang Froid | Grace Coxman | 2019 |
| Les Filles du docteur March | Marmee March | 2019 |
| Return to Jurassic Park | Self | 2011 |
| More Things That Happened | Susan Blue | 2007 |
| Marriage Story: From the Pages to the Performances | Self | 2019 |
| Blue Velvet: The Lost Footage | Sandy Williams | 2011 |
| Jurassic World : Le Monde d’après | Ellie Sattler | 2022 |
| Crazy, Not Insane | Literary Voice of Dorothy Lewis (voice) | 2020 |
| Happy Endings | Audrey Constantine | 1983 |
| The Son | Kate | 2022 |
| Bastard Out of Carolina | Narrator (voice) | 1996 |
| The Number of Completion | Self | 2017 |
| The Man with the Gray Elevated Hair | Self | 2017 |
| A Bloody Finger in Your Mouth | Self | 2017 |
| Rabbit Ears - The Song of Sacajawea | Narrator (voice) | 1993 |
| The Making of "Marriage Story" | Self | 2020 |
| Carole & Grey | Laura Dern | 2024 |
| David Lynch, une énigme à Hollywood | Self - Actor | 2025 |
| Love, Death, Elvis & Oz: The Making of Wild at Heart | | 2004 |
| Production Story: Fat Man and Little Boy | Self | 1989 |
| Is This Thing On? | Tess Novak | 2025 |
| Morning | Cathy | |
| Pris au piège - Caught Stealing | Hank's Mom (uncredited) | 2025 |
| Jay Kelly : Le making-of | Self - Liz | 2025 |
