Film | Rôle | Année |
|---|
| Sailor et Lula | Perdita Durango | 1990 |
| Spaceman | Commissioner Tůmová | 2024 |
| Blue Velvet | Dorothy Vallens | 1986 |
| The Tulse Luper Suitcases, Part 2: Vaux to the Sea | Madame Moitessier | 2004 |
| Two Lovers | Ruth Kraditor | 2008 |
| Rossellini visto da Rossellini | Self (archive footage) | 1993 |
| État second | Laura Klein | 1993 |
| Cat Person | Dr. Enid Zabala | 2023 |
| Nos funérailles | Clara Tempio | 1996 |
| Cousins | Maria Hardy | 1989 |
| Wyatt Earp | Big Nose Kate | 1994 |
| Contamination : la menace venue d'ailleurs | Carla Plume | 2008 |
| La mort vous va si bien | Lisle von Rhuman | 1992 |
| Scandaleusement célèbre | Marella Agnelli | 2006 |
| Empire | La Colombiana | 2002 |
| Un Mari de trop | Mrs. Greta Bollenbecker | 2008 |
| Roger Dodger | Joyce | 2002 |
| Problemista | Narrator (voice) | 2024 |
| Les Yeux noirs | Claudia (uncredited) | 1987 |
| Les Imposteurs | The Veiled Queen | 1998 |
| Ludwig van B. | Anna Marie Erdödy | 1994 |
| Senza Lucio | Self | 2015 |
| Heights | Liz | 2005 |
| The Pickle | Planet Cleveland Woman (uncredited) | 1993 |
| Il Pap'occhio | self | 1980 |
| Zelly & Me | Mademoiselle Zelly | 1988 |
| Siesta | Marie | 1987 |
| Le Dernier Cow-boy | 'Countess' Martine | 2003 |
| La musique la plus triste du monde | Lady Helen Port-Huntley | 2003 |
| Soleil de nuit | Darya Greenwood | 1985 |
| Le Petit Chaperon rouge | Lady Jean | 1987 |
| Naya: Legend of the Golden Dolphin | Queen Maya (voice) | |
| La Fiesta del Chivo | Urania | 2006 |
| The Architect | Julia Waters | 2006 |
| La grande nuit | Gabriella | 1996 |
| My Dad Is 100 Years Old | Self / Alfred Hitchcock / David O. Selznick / Federico Fellini / Charlie Chaplin / Ingrid Bergman / Roberto Rossellini | 2006 |
| My Dog Tulip | Ms. Canvenini (voice) | 2010 |
| À la recherche du passé | Mrs. Kalman | 1998 |
| La Solitude des nombres premiers | Adele | 2010 |
| L'Innocent | Maria | 1993 |
| About Face: Supermodels Then and Now | Herself | 2012 |
| Ulysse, souviens-toi ! | Hyacinth | 2011 |
| La Chimère | Flora | 2023 |
| Les vrais durs ne dansent pas | Madeleine Regency | 1987 |
| Louis I., König der Schafe | Narrator (voice) | 2023 |
| Il resto del Pap'occhio | self | 1980 |
| Poulet aux Prunes | Parvine | 2011 |
| A Matter of Time | Sister Pia | 1976 |
| Italia : le feu, la cendre | Self - Narrator (voice) | 2023 |
| 3 fois 20 ans | Mary | 2011 |
| La créativité peut-elle sauver le monde ? | Self | 2024 |
| Mysteries of Love | Self | 2002 |
| Du vent dans mes mollets | Madame Trebla | 2012 |
| Le Pré | Eugenia | 1979 |
| Enemy | Mother | 2014 |
| Filthy Gorgeous | Antonia | 2007 |
| Lies of the Twins | Rachel Marks | 1991 |
| Il Cielo Cade | Katchen | 2000 |
| Don Quixote | The Duchess | 2000 |
| Le crime du siècle | Anna Hauptmann | 1996 |
| Animals Distract Me | Self | 2011 |
| A Season with Isabella Rossellini | Self | 2023 |
| Send Me to the 'Lectric Chair | | 2009 |
| Il était une fois... « Rome, ville ouverte » | Self | 2006 |
| Flat Love | Narrator (voice) | 2009 |
| Ivory Hunters | Maria DiConti | 1990 |
| BAM150 | Self | 2012 |
| Sex | Self | 1992 |
| Isabella Rossellini - De la vie d'un papillon | Self | 2010 |
| Joy | Trudy | 2015 |
| Fox Film | Narrator | 2020 |
| Closet Monster | Buffy (voice) | 2016 |
| Des trous dans la tête | Interlocuter | 2007 |
| Ingrid | Self | 1996 |
| Je suis Ingrid | Self | 2015 |
| No Frank in Lumberton | Self | 1988 |
| The 1000 Eyes of Dr Maddin | | 2015 |
| Isabella Rossellini's Green Porno Live | Self | 2015 |
| Seduce Me | | 2010 |
| Viva Ingrid! | Narrator (voice) | 2015 |
| The Temptation Of Gracie | | |
| The Last Jews of Libya | Herself | 2007 |
| Dames galantes | Victoire | 1990 |
| Beyond Wiseguys: Italian Americans & the Movies | | 2008 |
| Seduce Me: Noah's Ark | | 2010 |
| Dennis Hopper - Rebelle d'Hollywood | Self | 2016 |
| Blue Velvet Revisited | Self | 2016 |
| Unanimal | Voice-over | 2025 |
| Soul of a Farmer | Self | 2021 |
| Vita et Virginia | Lady Sackville | 2019 |
| Le cinéma dans l'oeil de Magnum | Interviewee | 2017 |
| Così parlò De Crescenzo | | 2017 |
| La Traversée du désir | Self | 2009 |
| Leslie Howard: The Man Who Gave a Damn | Ingrid Bergman (voice) | 2015 |
| Trespassing Bergman | Self | 2013 |
| Les Indestructibles 2 | Ambassador (voice) | 2018 |
| Notes on My Father: An Interview with Isabella Rossellini | | 2005 |
| Larger than Life: The Kevyn Aucoin Story | Self | 2017 |
| Il était une fois... « Les enchaînés » | Self | 2009 |
| Voom Portraits | Self | 2007 |
| Croce e Delizia | Henriette | 1995 |
| Caccia alla vedova | | 1991 |
| Silent Retreat | Michelle Keaton | |
| The Rabbit Hunters | | 2020 |
| Blue Velvet: The Lost Footage | Dorothy Vallens | 2011 |
| Helmut Newton, l'effronté | Self | 2020 |
| Darwin, What? | | 2020 |
| The Rossellinis | Self | 2021 |
| Paolo Conte - Via con me | Self | 2020 |
| Kort möte med familjen Rossellini | Self | 1953 |
| Tales from the Crypt: The Robert Zemeckis Collection | Betty Spinelli | 1999 |
| Paavo, fem rätter och ett liv | Self | 2010 |
| Pas de Deux: Making 'White Nights' | Self | 2006 |
| Roberto Rossellini: Frammenti e Battute | Self | 2001 |
| Roberto Rossellini: Il mestiere di uomo | Self - Presenter | 1997 |
| Pompei - Eros e mito | self | 2020 |
| Corona Film Club | Self | 2021 |
| A Winter Fable | | 2017 |
| Silent Life: The Story of the Lady in Black | Gabriella Guglielmi | 2023 |
| Nono, the Zigzag Kid | Lola Ciperola | 2012 |
| Land of Dreams | Jane | 2022 |
| King of the Corner | Rachel Spivak | 2004 |
| Rossellini | Self | 1990 |
| Koko: The Gorilla Who Talks to People | Self (archive footage) | 2016 |
| Marcel, le Coquillage (avec ses chaussures) | Connie (voice) | 2022 |
| Kill Gil - Vol. 1 | self | 2005 |
| Conclave | Sister Agnes | 2024 |
| Unknown Beauty: François Nars | Self | 2023 |
| L'era legale | Self | 2011 |
| David Lynch, une énigme à Hollywood | Self - Actor | 2025 |
| The Duchess and I | Suzanne Blum | |
| Sartoria Tirelli - Vestire il cinema | Self | 2006 |
| Blue Peanuts | Lucy (Voice) | 1987 |
| The Painted Bride | (voice) | |
| Sequestered - Inside Conclave | Self | |
| All Star Tribute to Ingrid Bergman | Self | 1979 |
| Madonna: The Making of SEX Book | Self | 1992 |
| Roberto Rossellini - Più di una vita | Isabella Rossellini | 2025 |
| Pas de sexe s'il vous plait ! | | 2018 |
| The Odyssey | Athena | 1997 |
| The Tulse Luper Suitcases, Part 1: The Moab Story | Madame Moitessier | 2003 |
| The Tulse Luper Suitcases, Part 3: From Sark to the Finish | Madame Moitessier | 2005 |
| A Life in Suitcases: A History of Tulse Luper | Madame Moitessier | 2005 |
| Morceaux de Cannes | | 2021 |
