Casting | Rôle |
|---|
| 鈴木勝吾 | William James Moriarty |
| 平野良 | Sherlock Holmes |
| 久保田秀敏 | Albert James Moriarty (Op. Team) |
| 泰江和明 | Albert James Moriarty (Reprise Team) |
| 山本一慶 | Louis James Moriarty (Op. Team) |
| 業務提携 | Louis James Moriarty (Reprise Team) |
| 佐々木 崇 | Sebastian Moran |
| Yugo Miyajima | Fred Pollock (Op. Team) |
| Seiji Shinya | Fred Pollock (Reprise Team) |
| 鎌苅健太 | John H. Watson (Op. Team) |
| Shinichi Hashimoto | John H. Watson (Reprise Team) |
| 七木奏音 | Miss Hudson |
| 髙木俊 | George Lestrade/Jefferson Hope (Op. Team) |
| Junichi Ito | George Lestrade/Jefferson Hope (Reprise Team) |
| Eisei Yoshida | Baron Leonard Thomas Dublin |
| 小南光司 | Blitz Enders (Op. Team) |
| 内藤 光佑 | Blitz Enders (Reprise Team) |