Casting | Rôle |
|---|
| Dermot Mulroney | Dante (voice) |
| James Cromwell | Virgil (voice) |
| Olivia D'Abo | Beatrice (voice) |
| Martha Plimpton | Celia / Lobbyist Singer / Lizzie Borden (voice) |
| Tony Abatemarco | Lying Defendant / Farinata (voice) |
| Scott Adsit | Judge Minos / Paolo / Hirohito / Copter Pilot (voice) |
| Matt Besser | Metallica Defendant / L. Ron Hubbard (voice) |
| Bill Chott | Giaccio 'El Gordo' / Calvacanti / Stalin (voice) |
| Andy Daly | Lucan / 'Right On' Glutton / Jim Jones / Airport Screener / Ulysses' Naysayer (voice) |
| Tony Hale | Ovid / Real Estate Broker / Pope Nicholas 3rd (voice) |
| Tom Hallick | George Sanders / Lobbyist (voice) |
| Janet Varney | Teacher / Cleopatra / City of Dis Intercom / Ulysses' Usher (voice) |
| Paul Zaloom | Homer / God / Officer Chiron / Southern Lobbyist / Airport Security / Caiaphas / Ulysses' Crew / Macmud / Insider Trader #1 / Nicole Ceausescu / Lucifer (voice) |
| Mike Coleman | Charon / Phlegyas / Senator / Dick Cheney (voice) |
| Brandon Johnson | Irate Driver / Mounted Policeman / Pimp #1 / Pimp #3 / Airport Security (voice) |
| Matt Walsh | Mussolini / Fox Reporter / Airport Security Pursuer (voice) |
| Dana Snyder | Strom Thurmond / Ulysses (voice) |
