Casting | Rôle |
|---|
| Clint Eastwood | Manco |
| Lee Van Cleef | Col. Douglas Mortimer |
| Gian Maria Volonté | El Indio |
| Luigi Pistilli | Groggy, Member of Indio's Gang |
| Klaus Kinski | Juan Wild - The Hunchback |
| Joseph Egger | Old Prophet |
| Panos Papadopulos | Sancho Perez, Member of Indio's Gang |
| Mara Krupp | Mary |
| Benito Stefanelli | Luke 'Hughie' |
| Roberto Camardiel | Tucumcari Station Clerk |
| Aldo Sambrell | Cuchillo |
| Luis Rodríguez | Manuel, Member of Indio's Gang |
| Tomás Blanco | Tucumcari Sheriff |
| Lorenzo Robledo | Tomaso, Indio's Traitor |
| Sergio Mendizábal | Tucumcari Bank Manager |
| Dante Maggio | Carpenter in Cell with El Indio |
| Diana Rabito | Callaway's Beautiful Girl in Tub |
| Giovanni Tarallo | Santa Cruz Telegraphist |
| Mario Meniconi | Train Conductor |
| Mario Brega | Niño, Member of Indio's Gang |
| José Terrón | Guy Calloway, Mortimer's 1st Criminal (uncredited) |
| José Marco | 'Baby' Red Cavanaugh (uncredited) |
| Werner Abrolat | Slim, Member of Indio's Gang (uncredited) |
| Frank Braña | Blackie, Member of Indio's Gang (uncredited) |
| José Canalejas | Chico, Member of Indio's Gang (uncredited) |
| Antonio Molino Rojo | Frisco, Member of Indio's Gang (uncredited) |
| Jesús Guzmán | Carpetbagger on Train (uncredited) |
| Ricardo Palacios | Tucumcari Saloon Keeper (uncredited) |
| Guillermo Méndez | White Rocks Sheriff (uncredited) |
| Rosemary Dexter | Mortimer's Sister (uncredited) |
| Peter Lee Lawrence | Mortimer's Brother-in-Law (uncredited) |
| Kurt Zips | Hotel Manager (uncredited) |
| Enrique Navarro | (uncredited) |
| Bruno Corazzari | Poker Player (uncredited) |
| Carlo Simi | El Paso Bank Manager (uncredited) |
| Antoñito Ruiz | Fernando (uncredited) |
| Román Ariznavarreta | Half-Shaved Bounty Hunter (uncredited) |
| Joseph Bradley | El Paso Tavern Keeper (uncredited) |
| Fernando Di Leo | Cigar Smoking Card Player (uncredited) |
| Diana Faenza | Tomaso's Wife (uncredited) |
| Eduardo García | Member of Indio's Gang (uncredited) |
| Maurizio Graf | The Balladeer (voice) (uncredited) |
| Francesca Leone | Tomaso's Baby (uncredited) |
| Sergio Leone | Whistling Bounty Hunter (voice) (uncredited) |
| Rafael López | (uncredited) |
| Antonio Palombi | Bartender (uncredited) |
| Aldo Ricci | (uncredited) |
| Enrique Santiago | Miguel, Member of Indio's Gang (uncredited) |
| Edmondo Tieghi | 2nd Agua Caliente Villager Watching Monco (uncredited) |
| Antonio Montoya | Paco, Member of Indio's Gang (as José Montoya) |
